human FLT3LG shRNA silencing AAV

Cat. No: shAAV-209164

Availability: 4-5 weeks

Name: AAV-h-FLT3LG-shRNA

This is an AAV expressing shRNA for silencing of Human FLT3LG.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: FLT3LG
Gene Name: fms related tyrosine kinase 3 ligand
Gene ID: 2323
Gene Synonyms: FL; FLT3L
ORF Size: 462 bp
RefSeq#: NM_001459
Gene Description: Dendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen-specific immune responses. FLT3LG controls the development of DCs and is particularly important for plasmacytoid DCs and CD8 (see MIM 186910)-positive classical DCs and their CD103 (ITGAE; MIM 604682)-positive tissue counterparts (summary by Sathaliyawala et al., 2010 (PubMed 20933441)).(supplied by OMIM, Jan 2011)
UniGene ID: Hs.428
HGNC ID: HGNC:3766