human FLI1 shRNA silencing AAV

Cat. No: shAAV-209083

Availability: 4-5 weeks

Name: AAV-h-FLI1-shRNA

This is an AAV expressing shRNA for silencing of Human FLI1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: FLI1
Gene Name: Fli-1 proto-oncogene, ETS transcription factor
Gene ID: 2313
Gene Synonyms: EWSR2; SIC-1
ORF Size: 1359 bp
RefSeq#: NM_002017
Gene Description: FLI1 encodes a transcription factor containing an ETS DNA-binding domain. The gene can undergo a t(11;22)(q24;q12) translocation with the Ewing sarcoma gene on chromosome 22, which results in a fusion gene that is present in the majority of Ewing sarcoma cases. An acute lymphoblastic leukemia-associated t(4;11)(q21;q23) translocation involving this gene has also been identified. Alternative splicing results in multiple transcript variants.
UniGene ID: Hs.504281
HGNC ID: HGNC:3749