human FHL2 shRNA silencing AAV

Cat. No: shAAV-209011

Availability: 4-5 weeks

Name: AAV-h-FHL2-shRNA

This is an AAV expressing shRNA for silencing of Human FHL2.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: FHL2
Gene Name: four and a half LIM domains 2
Gene ID: 2274
Gene Synonyms: AAG11; DRAL; FHL-2; SLIM-3; SLIM3
ORF Size: 840 bp
RefSeq#: NM_001450
Gene Description: FHL2 encodes a member of the four-and-a-half-LIM-only protein family. Family members contain two highly conserved, tandemly arranged, zinc finger domains with four highly conserved cysteines binding a zinc atom in each zinc finger. This protein is thought to have a role in the assembly of extracellular membranes. Also, this gene is down-regulated during transformation of normal myoblasts to rhabdomyosarcoma cells and the encoded protein may function as a link between presenilin-2 and an intracellular signaling pathway. Multiple alternatively spliced variants, encoding the same protein, have been identified.
UniGene ID: Hs.443687
HGNC ID: HGNC:3703