human FGF5 shRNA silencing AAV

Cat. No: shAAV-208974

Availability: 6-8 weeks

Name: AAV-h-FGF5-shRNA

This is an AAV expressing shRNA for silencing of Human FGF5.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: FGF5
Gene Name: fibroblast growth factor 5
Gene ID: 2250
Gene Synonyms: HBGF-5; Smag-82; TCMGLY
ORF Size: 807 bp
RefSeq#: NM_004464
Gene Description: FGF5 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified as an oncogene, which confers transforming potential when transfected into mammalian cells. Targeted disruption of the homolog of this gene in mouse resulted in the phenotype of abnormally long hair, which suggested a function as an inhibitor of hair elongation. Alternatively spliced transcript variants encoding different isoforms have been identified.
UniGene ID: Hs.37055
HGNC ID: HGNC:3683