human FGF3 shRNA silencing AAV

Cat. No: shAAV-208971

Availability: 6-8 weeks

Name: AAV-h-FGF3-shRNA

This is an AAV expressing shRNA for silencing of Human FGF3.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: FGF3
Gene Name: fibroblast growth factor 3
Gene ID: 2248
Gene Synonyms: HBGF-3; INT2
ORF Size: 720 bp
RefSeq#: NM_005247
Gene Description: FGF3 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified by its similarity with mouse fgf3/int-2, a proto-oncogene activated in virally induced mammary tumors in the mouse. Frequent amplification of this gene has been found in human tumors, which may be important for neoplastic transformation and tumor progression. Studies of the similar genes in mouse and chicken suggested the role in inner ear formation.
UniGene ID: Hs.37092
HGNC ID: HGNC:3681