human FCRLA shRNA silencing AAV

Cat. No: shAAV-208884

Availability: 6-8 weeks

Name: AAV-h-FCRLA-shRNA

This is an AAV expressing shRNA for silencing of Human FCRLA.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: FCRLA
Gene Name: Fc receptor like A
Gene ID: 84824
Gene Synonyms: FCRL; FCRL1; FCRLb; FCRLc1; FCRLc2; FCRLd; FCRLe; FCRLM1; FCRLX; FCRX; FREB
ORF Size: 1131 bp
RefSeq#: NM_032738
Gene Description: FCRLA encodes a protein similar to receptors for the Fc fragment of gamma immunoglobulin (IgG). These receptors, referred to as FCGRs, mediate the destruction of IgG-coated antigens and of cells induced by antibodies. This encoded protein is selectively expressed in B cells, and may be involved in their development. This protein may also be involved in the development of lymphomas. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.
UniGene ID: Hs.266331
HGNC ID: HGNC:18504