human FBXL3 shRNA silencing AAV

Cat. No: shAAV-208761

Availability: 4-5 weeks

Name: AAV-h-FBXL3-shRNA

This is an AAV expressing shRNA for silencing of Human FBXL3.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: FBXL3
Gene Name: F-box and leucine rich repeat protein 3
Gene ID: 26224
Gene Synonyms: FBL3; FBL3A; FBXL3A
ORF Size: 1287 bp
RefSeq#: NM_012158
Gene Description: FBXL3 encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains several tandem leucine-rich repeats and is localized in the nucleus.
UniGene ID: Hs.508284
HGNC ID: HGNC:13599