human FASN shRNA silencing AAV

Cat. No: shAAV-208722

Availability: 4-5 weeks

Name: AAV-h-FASN-shRNA

This is an AAV expressing shRNA for silencing of Human FASN.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: FASN
Gene Name: fatty acid synthase
Gene ID: 2194
Gene Synonyms: FAS; OA-519; SDR27X1
ORF Size: 7536 bp
RefSeq#: NM_004104
Gene Description: The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha.
UniGene ID: Hs.83190
HGNC ID: HGNC:3594