human FARS2 shRNA silencing AAV

Cat. No: shAAV-208716

Availability: 4-5 weeks

Name: AAV-h-FARS2-shRNA

This is an AAV expressing shRNA for silencing of Human FARS2.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: FARS2
Gene Name: phenylalanyl-tRNA synthetase 2, mitochondrial
Gene ID: 10667
Gene Synonyms: COXPD14; FARS1; HSPC320; PheRS; SPG77
ORF Size: 1356 bp
RefSeq#: NM_006567
Gene Description: Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. This gene encodes a phenylalanine-tRNA synthetase (PheRS) localized to the mitochondrion which consists of a single polypeptide chain, unlike the (alpha-beta)2 structure of the prokaryotic and eukaryotic cytoplasmic forms of PheRS. Structure analysis and catalytic properties indicate mitochondrial PheRSs may constitute a class of PheRS distinct from the enzymes found in prokaryotes and in the eukaryotic cytoplasm.
UniGene ID: Hs.484547
HGNC ID: HGNC:21062