human FANCM shRNA silencing AAV

Cat. No: shAAV-208707

Availability: 4-5 weeks

Name: AAV-h-FANCM-shRNA

This is an AAV expressing shRNA for silencing of Human FANCM.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: FANCM
Gene Name: Fanconi anemia complementation group M
Gene ID: 57697
Gene Synonyms: FAAP250; KIAA1596
ORF Size: 6144 bp
RefSeq#: NM_020937
Gene Description: The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group M.
UniGene ID: Hs.509229
HGNC ID: HGNC:23168