human RHEB shRNA silencing AAV

Cat. No: shAAV-208542

Availability: 4-5 weeks

Name: AAV-h-RHEB-shRNA

This is an AAV expressing shRNA for silencing of Human RHEB.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: RHEB
Gene Name: Ras homolog enriched in brain
Gene ID: 6009
Gene Synonyms: RHEB2
ORF Size: 555 bp
RefSeq#: NM_005614
Gene Description: RHEB is a member of the small GTPase superfamily and encodes a lipid-anchored, cell membrane protein with five repeats of the RAS-related GTP-binding region. This protein is vital in regulation of growth and cell cycle progression due to its role in the insulin/TOR/S6K signaling pathway. The protein has GTPase activity and shuttles between a GDP-bound form and a GTP-bound form, and farnesylation of the protein is required for this activity. Three pseudogenes have been mapped, two on chromosome 10 and one on chromosome 22.
UniGene ID: Hs.283521
HGNC ID: HGNC:10011