human FADS1 shRNA silencing AAV

Cat. No: shAAV-208258

Availability: 4-5 weeks

Name: AAV-h-FADS1-shRNA

This is an AAV expressing shRNA for silencing of Human FADS1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: FADS1
Gene Name: fatty acid desaturase 1
Gene ID: 3992
Gene Synonyms: D5D; FADS6; FADSD5; LLCDL1; TU12
ORF Size: 1335 bp
RefSeq#: NM_013402
Gene Description: FADS1 is a member of the fatty acid desaturase (FADS) gene family. Desaturase enzymes regulate unsaturation of fatty acids through the introduction of double bonds between defined carbons of the fatty acyl chain. FADS family members are considered fusion products composed of an N-terminal cytochrome b5-like domain and a C-terminal multiple membrane-spanning desaturase portion, both of which are characterized by conserved histidine motifs. This gene is clustered with family members FADS1 and FADS2 at 11q12-q13.1; this cluster is thought to have arisen evolutionarily from gene duplication based on its similar exon/intron organization.
UniGene ID: Hs.503546
HGNC ID: HGNC:3574