human F2RL1 shRNA silencing AAV

Cat. No: shAAV-208224

Availability: 4-5 weeks

Name: AAV-h-F2RL1-shRNA

This is an AAV expressing shRNA for silencing of Human F2RL1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: F2RL1
Gene Name: F2R like trypsin receptor 1
Gene ID: 2150
Gene Synonyms: GPR11; PAR2
ORF Size: 1194 bp
RefSeq#: NM_005242
Gene Description: Coagulation factor II (thrombin) receptor-like 1 (F2RL1) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL1 is also a member of the protease-activated receptor family. It is activated by trypsin, but not by thrombin. It is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. The F2RL1 gene contains two exons and is widely expressed in human tissues. The predicted protein sequence is 83% identical to the mouse receptor sequence.
UniGene ID: Hs.154299
HGNC ID: HGNC:3538