human ETFDH shRNA silencing AAV

Cat. No: shAAV-208135

Availability: 4-5 weeks

Name: AAV-h-ETFDH-shRNA

This is an AAV expressing shRNA for silencing of Human ETFDH.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: ETFDH
Gene Name: electron transfer flavoprotein dehydrogenase
Gene ID: 2110
Gene Synonyms: ETFQO; MADD
ORF Size: 1854 bp
RefSeq#: NM_004453
Gene Description: Electron-transferring-flavoprotein dehydrogenase in the inner mitochondrial membrane accepts electrons from electron-transfer flavoprotein which is located in the mitochondrial matrix and reduces ubiquinone in the mitochondrial membrane. The protein is synthesized as a 67-kDa precursor which is targeted to mitochondria and processed in a single step to a 64-kDa mature form located in the mitochondrial membrane. Deficiency in electron-transferring-flavoprotein dehydrogenase have been demonstrated in some patients with type II glutaricacidemia.
UniGene ID: Hs.155729
HGNC ID: HGNC:3483