human ETF1 shRNA silencing AAV

Cat. No: shAAV-208132

Availability: 4-5 weeks

Name: AAV-h-ETF1-shRNA

This is an AAV expressing shRNA for silencing of Human ETF1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: ETF1
Gene Name: eukaryotic translation termination factor 1
Gene ID: 2107
Gene Synonyms: D5S1995; ERF; ERF1; RF1; SUP45L1; TB3-1
ORF Size: 1314 bp
RefSeq#: NM_004730
Gene Description: ETF1 encodes a class-1 polypeptide chain release factor. The encoded protein plays an essential role in directing termination of mRNA translation from the termination codons UAA, UAG and UGA. This protein is a component of the SURF complex which promotes degradation of prematurely terminated mRNAs via the mechanism of nonsense-mediated mRNA decay (NMD). Alternate splicing results in coding and non-coding transcript variants. Pseudogenes of this gene are found on chromosomes 5, 7 and X.
UniGene ID: Hs.483494
HGNC ID: HGNC:3477