human ESRRA shRNA silencing AAV

Cat. No: shAAV-208121

Availability: 4-5 weeks

Name: AAV-h-ESRRA-shRNA

This is an AAV expressing shRNA for silencing of Human ESRRA.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: ESRRA
Gene Name: estrogen related receptor alpha
Gene ID: 2101
Gene Synonyms: ERR1; ERRa; ERRalpha; ESRL1; NR3B1
ORF Size: 1272 bp
RefSeq#: NM_004451
Gene Description: ESRRA is a nuclear receptor that is closely related to the estrogen receptor. This protein acts as a site-specific transcription regulator and has been also shown to interact with estrogen and the transcripton factor TFIIB by direct protein-protein contact. The binding and regulatory activities of this protein have been demonstrated in the regulation of a variety of genes including lactoferrin, osteopontin, medium-chain acyl coenzyme A dehydrogenase (MCAD) and thyroid hormone receptor genes. A processed pseudogene of ESRRA is located on chromosome 13q12.1.
UniGene ID: Hs.110849
HGNC ID: HGNC:3471