human ERCC3 shRNA silencing AAV

Cat. No: shAAV-208060

Availability: 6-8 weeks

Name: AAV-h-ERCC3-shRNA

This is an AAV expressing shRNA for silencing of Human ERCC3.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: ERCC3
Gene Name: ERCC excision repair 3, TFIIH core complex helicase subunit
Gene ID: 2071
Gene Synonyms: BTF2; GTF2H; RAD25; TFIIH; TTD2; XPB
ORF Size: 2349 bp
RefSeq#: NM_000122
Gene Description: ERCC3 is an ATP-dependent DNA helicase that functions in nucleotide excision repair and complements xeroderma pigmentosum group B mutations. It also is the 89 kDa subunit of basal transcription factor 2 (TFIIH) and thus functions in class II transcription.
UniGene ID: Hs.469872
HGNC ID: HGNC:3435