human EPHX1 shRNA silencing AAV

Cat. No: shAAV-207999

Availability: 4-5 weeks

Name: AAV-h-EPHX1-shRNA

This is an AAV expressing shRNA for silencing of Human EPHX1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: EPHX1
Gene Name: epoxide hydrolase 1
Gene ID: 2052
Gene Synonyms: EPHX; EPOX; HYL1; MEH
ORF Size: 1368 bp
RefSeq#: NM_000120
Gene Description: Epoxide hydrolase is a critical biotransformation enzyme that converts epoxides from the degradation of aromatic compounds to trans-dihydrodiols which can be conjugated and excreted from the body. Epoxide hydrolase functions in both the activation and detoxification of epoxides. Mutations in this gene cause preeclampsia, epoxide hydrolase deficiency or increased epoxide hydrolase activity. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
UniGene ID: Hs.89649
HGNC ID: HGNC:3401