human EPHA8 shRNA silencing AAV

Cat. No: shAAV-207992

Availability: 4-5 weeks

Name: AAV-h-EPHA8-shRNA

This is an AAV expressing shRNA for silencing of Human EPHA8.

Request a Quote

Please enter your email address and we'll be in touch with more information:

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: EPHA8
Gene Name: EPH receptor A8
Gene ID: 2046
Gene Synonyms: EEK; EK3; HEK3
ORF Size: 3015 bp
RefSeq#: NM_020526
Gene Description: EPHA8 encodes a member of the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. The protein encoded by this gene functions as a receptor for ephrin A2, A3 and A5 and plays a role in short-range contact-mediated axonal guidance during development of the mammalian nervous system.
UniGene ID: Hs.283613
HGNC ID: HGNC:3391