human EPAS1 shRNA silencing AAV

Cat. No: shAAV-207955

Availability: 4-5 weeks

Name: AAV-h-EPAS1-shRNA

This is an AAV expressing shRNA for silencing of Human EPAS1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: EPAS1
Gene Name: endothelial PAS domain protein 1
Gene ID: 2034
Gene Synonyms: bHLHe73; ECYT4; HIF2A; HLF; MOP2; PASD2
ORF Size: 2613 bp
RefSeq#: NM_001430
Gene Description: EPAS1 encodes a transcription factor involved in the induction of genes regulated by oxygen, which is induced as oxygen levels fall. The encoded protein contains a basic-helix-loop-helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels. Mutations in this gene are associated with erythrocytosis familial type 4.
UniGene ID: Hs.468410
HGNC ID: HGNC:3374