human EMD shRNA silencing AAV

Cat. No: shAAV-207871

Availability: 6-8 weeks

Name: AAV-h-EMD-shRNA

This is an AAV expressing shRNA for silencing of Human EMD.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: EMD
Gene Name: emerin
Gene ID: 2010
Gene Synonyms: EDMD; LEMD5; STA
ORF Size: 765 bp
RefSeq#: NM_000117
Gene Description: Emerin is a serine-rich nuclear membrane protein and a member of the nuclear lamina-associated protein family. It mediates membrane anchorage to the cytoskeleton. Dreifuss-Emery muscular dystrophy is an X-linked inherited degenerative myopathy resulting from mutation in the emerin gene.
UniGene ID: Hs.522823
HGNC ID: HGNC:3331