human EIF4E shRNA silencing AAV

Cat. No: shAAV-207777

Availability: 4-5 weeks

Name: AAV-h-EIF4E-shRNA

This is an AAV expressing shRNA for silencing of Human EIF4E.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: EIF4E
Gene Name: eukaryotic translation initiation factor 4E
Gene ID: 1977
Gene Synonyms: AUTS19; CBP; eIF-4E; EIF4E1; EIF4EL1; EIF4F
ORF Size: 654 bp
RefSeq#: NM_001968
Gene Description: EIF4E is a component of the eukaryotic translation initiation factor 4F complex, which recognizes the 7-methylguanosine cap structure at the 5' end of cellular mRNAs. The encoded protein aids in translation initiation by recruiting ribosomes to the mRNA. Association of this protein with the 4F complex is the rate-limiting step in translation initiation. Three transcript variants encoding different isoforms have been found for this gene.
UniGene ID: Hs.249718
HGNC ID: HGNC:3287