human EIF2C2 shRNA silencing AAV

Cat. No: shAAV-207721

Availability: 6-8 weeks

Name: AAV-h-EIF2C2-shRNA

This is an AAV expressing shRNA for silencing of Human AGO2.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: AGO2
Gene Name: argonaute 2, RISC catalytic component
Gene ID: 27161
Gene Synonyms: EIF2C2; Q10
ORF Size: 2580 bp
RefSeq#: NM_012154
Gene Description: EIF2C2 encodes a member of the Argonaute family of proteins which play a role in RNA interference. The encoded protein is highly basic, and contains a PAZ domain and a PIWI domain. It may interact with dicer1 and play a role in short-interfering-RNA-mediated gene silencing. Multiple transcript variants encoding different isoforms have been found for this gene.
UniGene ID: Hs.449415
HGNC ID: HGNC:3263