human EHD2 shRNA silencing AAV

Cat. No: shAAV-207680

Availability: 4-5 weeks

Name: AAV-h-EHD2-shRNA

This is an AAV expressing shRNA for silencing of Human EHD2.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: EHD2
Gene Name: EH domain containing 2
Gene ID: 30846
Gene Synonyms: PAST2
ORF Size: 1632 bp
RefSeq#: NM_014601
Gene Description: EHD2 encodes a member of the EH domain-containing protein family. These proteins are characterized by a C-terminal EF-hand domain, a nucleotide-binding consensus site at the N terminus and a bipartite nuclear localization signal. The encoded protein interacts with the actin cytoskeleton through an N-terminal domain and also binds to an EH domain-binding protein through the C-terminal EH domain. This interaction appears to connect clathrin-dependent endocytosis to actin, suggesting that this gene product participates in the endocytic pathway.
UniGene ID: Hs.631554
HGNC ID: HGNC:3243