human EEF2K shRNA silencing AAV

Cat. No: shAAV-207603

Availability: 4-5 weeks

Name: AAV-h-EEF2K-shRNA

This is an AAV expressing shRNA for silencing of Human EEF2K.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: EEF2K
Gene Name: eukaryotic elongation factor 2 kinase
Gene ID: 29904
Gene Synonyms: eEF-2K; HSU93850
ORF Size: 2178 bp
RefSeq#: NM_013302
Gene Description: EEF2K encodes a highly conserved protein kinase in the calmodulin-mediated signaling pathway that links activation of cell surface receptors to cell division. This kinase is involved in the regulation of protein synthesis. It phosphorylates eukaryotic elongation factor 2 (EEF2) and thus inhibits the EEF2 function. The activity of this kinase is increased in many cancers and may be a valid target for anti-cancer treatment.
UniGene ID: Hs.498892
HGNC ID: HGNC:24615