human EEF1D shRNA silencing AAV

Cat. No: shAAV-207600

Availability: 4-5 weeks

Name: AAV-h-EEF1D-shRNA

This is an AAV expressing shRNA for silencing of Human EEF1D.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: EEF1D
Gene Name: eukaryotic translation elongation factor 1 delta
Gene ID: 1936
Gene Synonyms: EF-1D; EF1D; FP1047
ORF Size: 1944 bp
RefSeq#: NM_001960
Gene Description: EEF1D encodes a subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This subunit, delta, functions as guanine nucleotide exchange factor. It is reported that following HIV-1 infection, this subunit interacts with HIV-1 Tat. This interaction results in repression of translation of host cell proteins and enhanced translation of viral proteins. Several alternatively spliced transcript variants encoding multiple isoforms have been found for this gene. Related pseudogenes have been defined on chromosomes 1, 6, 7, 9, 11, 13, 17, 19.
UniGene ID: Hs.686554
HGNC ID: HGNC:3211