human DRD3 shRNA silencing AAV

Cat. No: shAAV-207326

Availability: 6-8 weeks

Name: AAV-h-DRD3-shRNA

This is an AAV expressing shRNA for silencing of Human DRD3.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: DRD3
Gene Name: dopamine receptor D3
Gene ID: 1814
Gene Synonyms: D3DR; ETM1; FET1
ORF Size: 1203 bp
RefSeq#: NM_000796
Gene Description: DRD3 encodes the D3 subtype of the five (D1-D5) dopamine receptors. The activity of the D3 subtype receptor is mediated by G proteins which inhibit adenylyl cyclase. This receptor is localized to the limbic areas of the brain, which are associated with cognitive, emotional, and endocrine functions. Genetic variation in this gene may be associated with susceptibility to hereditary essential tremor 1. Alternative splicing of this gene results in transcript variants encoding different isoforms, although some variants may be subject to nonsense-mediated decay (NMD).
UniGene ID: Hs.121478
HGNC ID: HGNC:3024