human DPH2 shRNA silencing AAV

Cat. No: shAAV-207274

Availability: 4-5 weeks

Name: AAV-h-DPH2-shRNA

This is an AAV expressing shRNA for silencing of Human DPH2.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: DPH2
Gene Name: DPH2 homolog
Gene ID: 1802
Gene Synonyms: DPH2L2
ORF Size: 1470 bp
RefSeq#: NM_001384
Gene Description: DPH2 is one of two human genes similar to the yeast gene dph2. The yeast gene was identified by its ability to complement a diphthamide mutant strain, and thus probably functions in diphthamide biosynthesis. Diphthamide is a post-translationally modified histidine residue present in elongation factor 2 (EF2) that is the target of diphtheria toxin ADP-ribosylation. Two transcript variants encoding different isoforms have been found for this gene.
UniGene ID: Hs.632398
HGNC ID: HGNC:3004