human DPAGT1 shRNA silencing AAV

Cat. No: shAAV-207263

Availability: 4-5 weeks

Name: AAV-h-DPAGT1-shRNA

This is an AAV expressing shRNA for silencing of Human DPAGT1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: DPAGT1
Gene Name: dolichyl-phosphate N-acetylglucosaminephosphotransferase 1
Gene ID: 1798
Gene Synonyms: ALG7; CDG-Ij; CDG1J; CMS13; CMSTA2; D11S366; DGPT; DPAGT; DPAGT2; G1PT; GPT; UAGT; UGAT
ORF Size: 906 bp
RefSeq#: NM_001382
Gene Description: DPAGT1 is an enzyme that catalyzes the first step in the dolichol-linked oligosaccharide pathway for glycoprotein biosynthesis. This enzyme belongs to the glycosyltransferase family 4. This protein is an integral membrane protein of the endoplasmic reticulum. The congenital disorder of glycosylation type Ij is caused by mutation in the gene encoding this enzyme.
UniGene ID: Hs.524081
HGNC ID: HGNC:2995