human DOHH shRNA silencing AAV

Cat. No: shAAV-207240

Availability: 6-8 weeks

Name: AAV-h-DOHH-shRNA

This is an AAV expressing shRNA for silencing of Human DOHH.

Request a Quote

Please enter your email address and we'll be in touch with more information:

Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: DOHH
Gene Name: deoxyhypusine hydroxylase/monooxygenase
Gene ID: 83475
Gene Synonyms: hDOHH; HLRC1
ORF Size: 909 bp
RefSeq#: NM_031304
Gene Description: DOHH encodes a metalloenzyme that catalyzes the last step in the conversion of lysine to the unique amino acid hypusine in eukaryotic initiation factor 5A. The encoded protein hydroxylates deoxyhypusine to form hypusine in the mature eukaryotic initiation factor 5A protein. Alternative splicing results in multiple transcript variants.
UniGene ID: Hs.609012
HGNC ID: HGNC:28662