human DNM1L shRNA silencing AAV

Cat. No: shAAV-207202

Availability: 4-5 weeks

Name: AAV-h-DNM1L-shRNA

This is an AAV expressing shRNA for silencing of Human DNM1L.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: DNM1L
Gene Name: dynamin 1 like
Gene ID: 10059
Gene Synonyms: DLP1; DRP1; DVLP; DYMPLE; EMPF; EMPF1; HDYNIV
ORF Size: 2133 bp
RefSeq#: NM_012062
Gene Description: DNM1L is a member of the dynamin superfamily of GTPases. Members of the dynamin-related subfamily, including the S. cerevisiae proteins Dnm1 and Vps1, contain the N-terminal tripartite GTPase domain but do not have the pleckstrin homology or proline-rich domains. This protein establishes mitochondrial morphology through a role in distributing mitochondrial tubules throughout the cytoplasm. The gene has 3 alternatively spliced transcripts encoding different isoforms. These transcripts are alternatively polyadenylated.
UniGene ID: Hs.556296
HGNC ID: HGNC:2973