human DKK3 shRNA silencing AAV

Cat. No: shAAV-207028

Availability: 6-8 weeks

Name: AAV-h-DKK3-shRNA

This is an AAV expressing shRNA for silencing of Human DKK3.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: DKK3
Gene Name: dickkopf WNT signaling pathway inhibitor 3
Gene ID: 27122
Gene Synonyms: REIC; RIG
ORF Size: 1053 bp
RefSeq#: NM_015881
Gene Description: DKK3 encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene. Alternative splicing results in multiple transcript variants encoding the same protein.
UniGene ID: Hs.292156
HGNC ID: HGNC:2893