human DICER1 shRNA silencing AAV

Cat. No: shAAV-206990

Availability: 4-5 weeks

Name: AAV-h-DICER1-shRNA

This is an AAV expressing shRNA for silencing of Human DICER1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: DICER1
Gene Name: dicer 1, ribonuclease III
Gene ID: 23405
Gene Synonyms: DCR1; Dicer; Dicer1e; HERNA; K12H4.8-LIKE; MNG1; RMSE2
ORF Size: 5769 bp
RefSeq#: NM_030621
Gene Description: DICER1 encodes a protein possessing an RNA helicase motif containing a DEXH box in its amino terminus and an RNA motif in the carboxy terminus. The encoded protein functions as a ribonuclease and is required by the RNA interference and small temporal RNA (stRNA) pathways to produce the active small RNA component that represses gene expression. Alternative splicing results in multiple transcript variants.
UniGene ID: Hs.87889
HGNC ID: HGNC:17098