human DERL2 shRNA silencing AAV

Cat. No: shAAV-206887

Availability: 4-5 weeks

Name: AAV-h-DERL2-shRNA

This is an AAV expressing shRNA for silencing of Human DERL2.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: DERL2
Gene Name: derlin 2
Gene ID: 51009
Gene Synonyms: CGI-101; derlin-2; DERtrin-2; F-LAN-1; F-LANa; FLANa
ORF Size: 720 bp
RefSeq#: NM_016041
Gene Description: Proteins that are unfolded or misfolded in the endoplasmic reticulum (ER) must be refolded or degraded to maintain the homeostasis of the ER. DERL2 is involved in the degradation of misfolded glycoproteins in the ER (Oda et al., 2006 (PubMed 16449189)).(supplied by OMIM, Mar 2008)
UniGene ID: Hs.286131
HGNC ID: HGNC:17943