human DEFB118 shRNA silencing AAV

Cat. No: shAAV-206832

Availability: 6-8 weeks

Name: AAV-h-DEFB118-shRNA

This is an AAV expressing shRNA for silencing of Human DEFB118.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: DEFB118
Gene Name: defensin beta 118
Gene ID: 117285
Gene Synonyms: C20orf63; DEFB-18; ESC42; ESP13.6
ORF Size: 372 bp
RefSeq#: NM_054112
Gene Description: DEFB118 encodes a member of the beta subfamily of defensins. Beta-defensins are antimicrobial peptides that protect tissues and organs from infection by a variety of microorganisms. Expression of this gene is regulated by androgen, and the encoded protein binds to sperm and exhibits antibacterial activity. DEFB118 is found in a cluster with other beta-defensin genes on the long arm of chromosome 20.
UniGene ID: Hs.274124
HGNC ID: HGNC:16196