human DCK shRNA silencing AAV

Cat. No: shAAV-206652

Availability: 4-5 weeks

Name: AAV-h-DCK-shRNA

This is an AAV expressing shRNA for silencing of Human DCK.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: DCK
Gene Name: deoxycytidine kinase
Gene ID: 1633
ORF Size: 783 bp
RefSeq#: NM_000788
Gene Description: Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity.
UniGene ID: Hs.709
HGNC ID: HGNC:2704