human CYP2F1 shRNA silencing AAV

Cat. No: shAAV-206495

Availability: 6-8 weeks

Name: AAV-h-CYP2F1-shRNA

This is an AAV expressing shRNA for silencing of Human CYP2F1.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: CYP2F1
Gene Name: cytochrome P450 family 2 subfamily F member 1
Gene ID: 1572
Gene Synonyms: C2F1; CYP2F; CYPIIF1
ORF Size: 963 bp
RefSeq#: NM_000774
Gene Description: CYP2F1 encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to dehydrogenate 3-methylindole, an endogenous toxin derived from the fermentation of tryptophan, as well as xenobiotic substrates such as naphthalene and ethoxycoumarin. CYP2F1 is part of a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q.
UniGene ID: Hs.558318
HGNC ID: HGNC:2632