human CXCL1 shRNA silencing AAV

Cat. No: shAAV-206326

Availability: 6-8 weeks

Name: AAV-h-CXCL1-shRNA

This is an AAV expressing shRNA for silencing of Human CXCL1.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: CXCL1
Gene Name: C-X-C motif chemokine ligand 1
Gene ID: 2919
Gene Synonyms: FSP; GRO1; GROa; MGSA; MGSA-a; NAP-3; SCYB1
ORF Size: 324 bp
RefSeq#: NM_001511
Gene Description: CXCL1 encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signal through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils. Aberrant expression this protein is associated with the growth and progression of certain tumors. A naturally occurring processed form of this protein has increased chemotactic activity. Alternate splicing results in coding and non-coding variants of this gene. A pseudogene of this gene is found on chromosome 4.
UniGene ID: Hs.789
HGNC ID: HGNC:4602