human CX3CR1 shRNA silencing AAV

Cat. No: shAAV-206325

Availability: 6-8 weeks

Name: AAV-h-CX3CR1-shRNA

This is an AAV expressing shRNA for silencing of Human CX3CR1.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: CX3CR1
Gene Name: C-X3-C motif chemokine receptor 1
Gene ID: 1524
Gene Synonyms: CCRL1; CMKBRL1; CMKDR1; GPR13; GPRV28; V28
ORF Size: 1068 bp
RefSeq#: NM_001337
Gene Description: Fractalkine is a transmembrane protein and chemokine involved in the adhesion and migration of leukocytes. The protein encoded by this gene is a receptor for fractalkine. The encoded protein also is a coreceptor for HIV-1, and some variations in this gene lead to increased susceptibility to HIV-1 infection and rapid progression to AIDS. Four transcript variants encoding two different isoforms have been found for this gene.
UniGene ID: Hs.78913
HGNC ID: HGNC:2558