human CTH shRNA silencing AAV

Cat. No: shAAV-206233

Availability: 4-5 weeks

Name: AAV-h-CTH-shRNA

This is an AAV expressing shRNA for silencing of Human CTH.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: CTH
Gene Name: cystathionine gamma-lyase
Gene ID: 1491
ORF Size: 1218 bp
RefSeq#: NM_001902
Gene Description: CTH encodes a cytoplasmic enzyme in the trans-sulfuration pathway that converts cystathione derived from methionine into cysteine. Glutathione synthesis in the liver is dependent upon the availability of cysteine. Mutations in this gene cause cystathioninuria. Alternative splicing of this gene results in three transcript variants encoding different isoforms.
UniGene ID: Hs.19904
HGNC ID: HGNC:2501