human CRLF1 shRNA silencing AAV

Cat. No: shAAV-206024

Availability: 4-5 weeks

Name: AAV-h-CRLF1-shRNA

This is an AAV expressing shRNA for silencing of Human CRLF1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: CRLF1
Gene Name: cytokine receptor like factor 1
Gene ID: 9244
Gene Synonyms: CISS; CISS1; CLF; CLF-1; NR6; zcytor5
ORF Size: 1269 bp
RefSeq#: NM_004750
Gene Description: CRLF1 encodes a member of the cytokine type I receptor family. The protein forms a secreted complex with cardiotrophin-like cytokine factor 1 and acts on cells expressing ciliary neurotrophic factor receptors. The complex can promote survival of neuronal cells. Mutations in this gene result in Crisponi syndrome and cold-induced sweating syndrome.
UniGene ID: Hs.114948
HGNC ID: HGNC:2364