human CRADD shRNA silencing AAV

Cat. No: shAAV-205957

Availability: 4-5 weeks

Name: AAV-h-CRADD-shRNA

This is an AAV expressing shRNA for silencing of Human CRADD.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: CRADD
Gene Name: CASP2 and RIPK1 domain containing adaptor with death domain
Gene ID: 8738
Gene Synonyms: MRT34; RAIDD
ORF Size: 600 bp
RefSeq#: NM_003805
Gene Description: CRADD is a death domain (CARD/DD)-containing protein and has been shown to induce cell apoptosis. Through its CARD domain, this protein interacts with, and thus recruits, caspase 2/ICH1 to the cell death signal transduction complex that includes tumor necrosis factor receptor 1 (TNFR1A), RIPK1/RIP kinase, and numbers of other CARD domain-containing proteins.
UniGene ID: Hs.591016
HGNC ID: HGNC:2340