human CPT1A shRNA silencing AAV

Cat. No: shAAV-205937

Availability: 4-5 weeks

Name: AAV-h-CPT1A-shRNA

This is an AAV expressing shRNA for silencing of Human CPT1A.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: CPT1A
Gene Name: carnitine palmitoyltransferase 1A
Gene ID: 1374
Gene Synonyms: CPT1; CPT1-L; L-CPT1
ORF Size: 2271 bp
RefSeq#: NM_001876
Gene Description: The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
UniGene ID: Hs.503043
HGNC ID: HGNC:2328