human COPA shRNA silencing AAV
Category: AAV > shRNA-Silencing
Cat. No: shAAV-205757
Availability:
4-5 weeks
Name:
AAV-h-COPA-shRNA
This is an AAV expressing shRNA for silencing of Human COPA.
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Product Info
- Knockdown
- >70% knockdown of mRNA in cultured cells
Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- COPA
- Gene Name
- coatomer protein complex subunit alpha
- Gene ID
- 1314
- Gene Synonyms
- AILJK; HEP-COP
- ORF Size
- 3702 bp
- RefSeq#
- NM_004371
- Gene Description
- In eukaryotic cells, protein transport between the endoplasmic reticulum and Golgi compartments is mediated in part by non-clathrin-coated vesicular coat proteins (COPs). Seven coat proteins have been identified, and they represent subunits of a complex known as coatomer. The subunits are designated alpha-COP, beta-COP, beta-prime-COP, gamma-COP, delta-COP, epsilon-COP, and zeta-COP. The alpha-COP, encoded by COPA, shares high sequence similarity with RET1P, the alpha subunit of the coatomer complex in yeast. Also, the N-terminal 25 amino acids of alpha-COP encode the bioactive peptide, xenin, which stimulates exocrine pancreatic secretion and may act as a gastrointestinal hormone. Alternative splicing results in multiple splice forms encoding distinct isoforms.
- UniGene ID
- Hs.685025
- HGNC ID
- HGNC:2230
Related Products
Product | Cat No. |
---|---|
Ad-h-COPA | ADV-205757 |
Ad-m-COPA | ADV-255905 |
AAV-m-COPA-shRNA | shAAV-255905 |
Ad-h-COPA-shRNA | shADV-205757 |
Ad-m-COPA-shRNA | shADV-255905 |
Control Products
Product | Cat No. |
---|---|
AAV1-GFP-U6-shRNA | 7040 |
AAV2-GFP-U6-shRNA | 7041 |
AAV5-GFP-U6-shRNA | 7042 |
AAV6-GFP-U6-shRNA | 7043 |
AAV9-GFP-U6-shRNA | 7045 |
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