human COL3A1 shRNA silencing AAV

Cat. No: shAAV-205704

Availability: 6-8 weeks

Name: AAV-h-COL3A1-shRNA

This is an AAV expressing shRNA for silencing of Human COL3A1.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: COL3A1
Gene Name: collagen type III alpha 1 chain
Gene ID: 1281
Gene Synonyms: EDS4A
ORF Size: 3492 bp
RefSeq#: NM_000090
Gene Description: COL3A1 encodes the pro-alpha1 chains of type III collagen, a fibrillar collagen that is found in extensible connective tissues such as skin, lung, uterus, intestine and the vascular system, frequently in association with type I collagen. Mutations in this gene are associated with Ehlers-Danlos syndrome types IV, and with aortic and arterial aneurysms. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. (provided by R. Dalgleish, Feb 2008)
UniGene ID: Hs.708235
HGNC ID: HGNC:2201