human CNR1 shRNA silencing AAV

Cat. No: shAAV-205627

Availability: 6-8 weeks

Name: AAV-h-CNR1-shRNA

This is an AAV expressing shRNA for silencing of Human CNR1.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: CNR1
Gene Name: cannabinoid receptor 1
Gene ID: 1268
Gene Synonyms: CANN6; CB-R; CB1; CB1A; CB1K5; CB1R; CNR
ORF Size: 1419 bp
RefSeq#: NM_033181
Gene Description: CNR1 encodes one of two cannabinoid receptors. The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the guanine-nucleotide-binding protein (G-protein) coupled receptor family, which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. Multiple transcript variants encoding two different protein isoforms have been described for this gene.
UniGene ID: Hs.709067
HGNC ID: HGNC:2159