human CNO shRNA silencing AAV

Cat. No: shAAV-205602

Availability: 4-5 weeks

Name: AAV-h-CNO-shRNA

This is an AAV expressing shRNA for silencing of Human BLOC1S4.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: BLOC1S4
Gene Name: biogenesis of lysosomal organelles complex 1 subunit 4
Gene ID: 55330
Gene Synonyms: BCAS4L; BLOS4; CNO
ORF Size: 654 bp
RefSeq#: NM_018366
Gene Description: This intronless gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. A similar protein in mouse is a component of a protein complex termed biogenesis of lysosome-related organelles complex 1 (BLOC-1), and is a model for Hermansky-Pudlak syndrome. The encoded protein may play a role in intracellular vesicular trafficking.
UniGene ID: Hs.7570
HGNC ID: HGNC:24206