human CLOCK shRNA silencing AAV

Cat. No: shAAV-205493

Availability: 4-5 weeks

Name: AAV-h-CLOCK-shRNA

This is an AAV expressing shRNA for silencing of Human CLOCK.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: CLOCK
Gene Name: clock circadian regulator
Gene ID: 9575
Gene Synonyms: bHLHe8; KAT13D
ORF Size: 2541 bp
RefSeq#: NM_004898
Gene Description: CLOCK product regulates circadian rhythm and metabolism. The protein encodes a transcription factor of the basic helix-loop-helix (bHLH) family and a DNA binding histone acetyltransferase. Polymorphisms in this gene may be associated with behavioral changes in certain populations and with obesity and metabolic syndrome. Alternative splicing results in multiple transcript variants.
UniGene ID: Hs.436975
HGNC ID: HGNC:2082