human CLCN4 shRNA silencing AAV

Cat. No: shAAV-205352

Availability: 6-8 weeks

Name: AAV-h-CLCN4-shRNA

This is an AAV expressing shRNA for silencing of Human CLCN4.

Request a Quote

Please enter your email address and we'll be in touch with more information:

Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: CLCN4
Gene Name: chloride voltage-gated channel 4
Gene ID: 1183
Gene Synonyms: ClC-4; ClC-4A; CLC4; MRX15; MRX49
ORF Size: 2283 bp
RefSeq#: NM_001830
Gene Description: The CLCN family of voltage-dependent chloride channel genes comprises nine members (CLCN1-7, Ka and Kb) which demonstrate quite diverse functional characteristics while sharing significant sequence homology. Chloride channel 4 has an evolutionary conserved CpG island and is conserved in both mouse and hamster. This gene is mapped in close proximity to APXL (Apical protein Xenopus laevis-like) and OA1 (Ocular albinism type I), which are both located on the human X chromosome at band p22.3. The physiological role of chloride channel 4 remains unknown but may contribute to the pathogenesis of neuronal disorders. Alternate splicing results in two transcript variants that encode different proteins.
UniGene ID: Hs.495674
HGNC ID: HGNC:2022