human CHST11 shRNA silencing AAV

Cat. No: shAAV-205237

Availability: 4-5 weeks

Name: AAV-h-CHST11-shRNA

This is an AAV expressing shRNA for silencing of Human CHST11.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: CHST11
Gene Name: carbohydrate sulfotransferase 11
Gene ID: 50515
Gene Synonyms: C4ST; C4ST-1; C4ST1; HSA269537
ORF Size: 1059 bp
RefSeq#: NM_018413
Gene Description: CHST11 belongs to the sulfotransferase 2 family. It is localized to the golgi membrane, and catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage, and is distributed on the surfaces of many cells and extracellular matrices. A chromosomal translocation involving this gene and IgH, t(12;14)(q23;q32), has been reported in a patient with B-cell chronic lymphocytic leukemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
UniGene ID: Hs.17569
HGNC ID: HGNC:17422